New serum improves overall skin quality without side effects

To evaluate the efficacy and safety of a combination of antioxidants to protect the skin from environmental factors, researchers conducted a prospective, open-label study of vitamin C, astaxanthin, fermented turmeric, and vitamin E.¹ Koniski et al. found that the topical formulation provided an improvement in skin quality at the end of 12 weeks.

In this study, participants 35-60 with dry, normal, combination, and oily Fitzpatrick skin types I-VI with mild to moderate fine lines, wrinkles, hyperpigmentation, uneven skin tone It was conducted on healthy female participants of 1 year old. In a single-center, single-blind study, participants received a serum combining tetrahexyldecyl ascorbate (THD) (vitamin C), 3-O-ethylascorbic acid, fermented turmeric, astaxanthin, and tocopherol (vitamin E). It was applied twice daily for 12 weeks. This serum, Asta C Vitamin C Age Defense Serum by Dr. Whitney Bowe Beauty, is designed to combat free radical damage and improve the appearance of fine lines, wrinkles and hyperpigmentation.

Participants completed a one-week washout period using only a mild facial cleanser before the study began, and used their own moisturizer and sunscreen, but no other skin care products, during the study period. I did. Participants kept a home diary to track serum adherence. Clinical grading was performed at his 0, 2, and 12 weeks, and a 26-question self-awareness questionnaire was administered at his 2nd week and his 12th week.

Professional clinical photographs of the face, neck, and chest of 10 patients were taken at weeks 0, 2, and 12 and evaluated by clinical experts in categories such as overall skin appearance, skin aging, fine lines, and wrinkles. Visual and tactile grading was performed. Redness and elasticity. Of the 33 participants enrolled in the study, 32 completed the 12-week trial.

Evaluation of overall skin quality, overall aging appearance, overall fine lines, radiance, texture, redness, firmness, hyperpigmentation, and overall wrinkles on the face, neck and chest ranged from baseline to 12 By the second week there was visible improvement. It was statistically significant, showing a 10.4% improvement at week 2 and a 19.6% improvement at week 12, with his 100% of participants showing improvement.

Deep wrinkles showed a 9% improvement from baseline at week 12, with 81.3% of participants showing improvement. “Facial texture showed the greatest improvement, with 81.3% of participants decreasing clinical grade by 1 point or more.”

Skin firmness increased by 10.9% from baseline to week 12, with 81% of participants showing significant improvement in the appearance of elasticity and firmness. Skin radiance increased by 26.6% during the study period, with 100% of participants showing significant improvement.

Participants reported that the study vehicle was gentle enough for daily use and worked well with other skin care products. There were no serious adverse events. Limitations of this study include the small sample size and the absence of a control group.

“Overall, the current clinical studies demonstrate that Asta C is safe, well-tolerated, and effective in improving the appearance of fine lines, wrinkles, radiance, and hyperpigmentation, as well as overall skin quality. ,” conclude Konisky et al. . It was also gentle and effective on my delicate neck skin.

reference

1. Konisky H, Bowe WP, Yang P, Kobets K. Clinical evaluation of efficacy and tolerability of novel topical antioxidant formulations featuring vitamin C, astaxanthin, and fermented turmeric. jacosmet dermatol. 2023; 00:1-7. Doi: 10.1111/jocd.15967