August 14, 2023
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Disclosure: Piccoli and Wyatt do not report related financial disclosures.
Kidney disease is biologically regulated by sex, but may be culturally regulated by sex. It is well documented that there are sex differences and sex differences in the morbidity and prognosis of some kidney diseases, the prototype of which is lupus nephritis.
Access to healthcare may vary depending on social, economic and cultural factors. In many situations, women with renal failure are less likely than men to receive a kidney transplant, yet women are more likely to be living kidney donors.
These topics were part of a recent gathering hosted by Kidney Disease: Improving Outcomes Globally (KDIGO) as part of a controversial conference. The conference was a step forward in improving knowledge and capacity to support women with chronic kidney disease and those at risk of chronic kidney disease around the world.
The conference, held in Athens, Greece, brought together more than 75 experts from more than 30 countries, including adult and pediatric nephrologists, epidemiologists, obstetricians and gynecologists, neonatologists, nutritionists, midwives and patients. attended.
In addition to discussing gender differences in renal care and access, conference participants also discussed best practices for reproductive health and pregnancy complications in CKD women. These people may be experiencing reduced fertility, premature menopause, body image changes, and decreased sexual desire and satisfaction.
Pregnant women with CKD, even in the early stages, are at increased risk of premature birth and developing hypertension of pregnancy. The relationship between gestational hypertension, pre-eclampsia, and pregnancy complications is complex. Kidney disease is present in up to 20% of women with pre-eclampsia, but is often unrecognized, while pre-eclampsia and other pregnancy-related disorders are the most common causes of her AKI in the young. is one of woman.
In addition to scientific and clinical experts, four women with CKD described their own journeys through complicated pregnancies and shared their experiences as patients throughout the conference.
The conference highlighted the need for further research on many issues related to renal health in women, including gender and sex differences in the epidemiology, management, and outcomes of CKD. Female reproductive care across all stages of CKD. Use of biomarkers for early diagnosis of pre-eclampsia and management of high-risk pregnancies. Prevention of AKI during pregnancy. Timing of birth in high-risk pregnancies. Protection of future maternal and child health after pregnancies complicated by pre-eclampsia or related conditions. In each of these key discussions, the conference organizers identified important knowledge gaps that will aid future research.
Our common commitment to this meeting was to advance nephrology and conduct interdisciplinary discussions to improve care for women with CKD and their children. With the release of the final conference report later this year, KDIGO will support education and awareness programs to disseminate observations to guide future research to improve kidney health in women around the world. We are going to put a lot of effort into it.
- For more information:
- Dr. Georgina B. Piccoli, He is Associate Professor of Nephrology at the University of Angers, France and Head of the Department of Nephrology at the Center Hospitalier in Le Mans, France.
- Dr. Christina M. Wyatt, He is Associate Professor of Medicine and Nephrology at Duke Health and a member of the Duke Clinical Research Institute.