summary: Researchers have found associations between specific microbes in the infant’s gut and early cognitive developmental performance.
This exploratory study examined 56 infants and found that certain microbiome configurations were consistent with success on cognitive tests such as ‘point and stare’. These findings suggest a potential impact of the microbiome on cognitive development, but further research is essential.
- Infants with specific gut bacteria performed better on social attention tests.
- Specific patterns of brain activity upon hearing steady beats were associated with specific microbial levels and metabolic chemistries.
- We found no observable association between the microbiome during speech processing and cerebral blood flow in infants.
A small exploratory study showed that levels of certain types of microbes in the gut of infants were associated with performance on tests of early cognitive development.
Sebastian Hunter and colleagues at the University of British Columbia, Canada, have published these findings in an open-access journal. pro swan on August 9, 2023.
A large body of evidence has highlighted how the diverse microbial community, or microbiome, that naturally exists in the human gut is related to human health, including brain health.
Several studies in animals and humans have suggested links between the microbiome and early brain development, but how do differences in the infant microbiome translate into emerging cognitive differences? Few studies have examined whether it is associated with
To better understand these potential associations, Hunter and colleagues analyzed data from 56 infants aged 4 to 6 months. Each infant had completed at least one of her three assessments on various cognitive abilities, and researchers used fecal samples to assess gut microbiota.
Researchers found that infants who successfully completed a test of social attention known as “point and gaze” (which measures their ability to share their focus on an object with others) had higher levels of microbes in their bodies. I have found that there are many trends. actinomycete phylum, genus bifidobacteriaand genus Eggerterrathe amount of microorganisms is reduced. Firmicutes gate, don’t say genus, and Streptococcus Genus.
On the other hand, electroencephalographic measurements of brain activity in infants when listening to steady beats show that specific activity patterns associated with enhanced rhythm processing are associated with high and low levels of specific microbial types, and It has been shown to be associated with levels of specific metabolic chemistries. Microorganisms thought to be related to the development of the brain and spinal cord in previous studies.
No association was found between the microbiome and blood flow measurements in the infant brain in response to both forward and backward human speech recordings.
Overall, these findings are consistent with the idea that the microbiome can influence early cognitive development, but further studies are needed to confirm and clarify this role.
The authors further add: “In our small pilot study, we observed intriguing associations between the microbiome and brain function in early infancy. may be beneficial to
About this neurodevelopmental research news
author: Hana Abdullah
contact: Hannah Abdalla – PLOS
image: Image credited to Neuroscience News
Original research: open access.
“Babies, bugs and brains: how the early microbiome is linked to brain and behavioral development in young childrenby Sebastian Hunter et al. pro swan
Babies, bugs and brains: how the early microbiome is linked to brain and behavioral development in young children
A growing body of evidence points to a relationship between the gut-brain axis of the microbiota and neurodevelopment. Microbiota colonization occurs before many nervous systems mature and is associated with brain health. For this reason, it is hypothesized that early microbiome interactions along the gut-brain axis evolved to facilitate advanced cognitive function and behavior.
Here we conducted a pilot study with an interdisciplinary approach to test whether infant microbiota composition is related to measures of early cognitive development, particularly neural rhythm tracking. The distinction between verbal (forward speaking) and nonverbal (backward speaking). and attention of social co-workers.
Fecal samples were collected from 56 infants aged 4–6 months and sequenced by shotgun metagenomic sequencing. Of these, 44 performed a behavioral point-and-gaze test to measure joint attention.
Infants were evaluated for language discrimination using functional near-infrared spectroscopy (fNIRS, with available data for 25 infants), or neurorhythm tracking using electroencephalography (EEG, with available data for 15 infants). was examined).
Infants who passed the Point and Gaze test tended to have increased actinobacteria and decreased Firmicutes at the phylum level.and increase bifidobacteria and Eggerterra with a decrease in don’t say and Streptococcus at the genus level.
The measurement of neurorhythm tracking is bifidobacteria and positively rich Clostridium and enterococci It examines bacterial abundance and is positively associated with metabolic pathways, such as branched-chain amino acid biosynthesis and the pentose phosphate pathway, that may affect neurodevelopment. No association was found with fNIRS language discrimination measures.
Although the test was underpowered due to the small pilot sample size, we identified a potential association between the microbiome and measures of early cognitive development, which deserves further investigation.